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Treatment for NSCLC with Avastin Download

The Value of Support Groups

People living with cancer can learn and find the support they need when they read about or talk to others who are also living with cancer. Support groups provide an opportunity for people affected by cancer to help each other with the emotional and practical aspects of the disease.

Give and get support

Whether you have been diagnosed with cancer yourself or have a loved one with cancer, support groups can offer a confidential atmosphere in which to give and get support.

Where to find support groups

Many national organizations offer local and online support groups for people diagnosed with cancer and their family members or friends. Many of these organizations can refer you to a local chapter for more information.

Local hospitals and cancer clinics are also good sources for finding support groups. Doctors, nurses, or hospital social workers may have information about support groups, such as their location, size, type, and how often they meet. Hospitals have social services departments that can provide information about cancer support programs.

Below are some places to start your search for a local group:

American Lung Association*
Provides information on lung disease, research, and statistics, plus local programs and events.
1-800-LUNGUSA (1-800-586-4872)
www.lungusa.org

Lung Cancer Alliance*
Programs include an information and referral service, a peer-to-peer support network, and a national education and advocacy campaign.
1-800-298-2436
www.lungcanceralliance.org

National Lung Cancer Partnership*
Provides educational materials, inspirational stories and blogs, information on clinical trials, and additional resources.
1-608-233-7905
www.nationallungcancerpartnership.org

The Lung Cancer Online Foundation*
A directory of Internet information, services, support, and research for patients and families.
www.lungcanceronline.org

Cancer.net*
Web resource providing timely, oncologist-approved information from the American Society of Clinical Oncology to help patients and families make informed health care decisions.
1-888-651-3038
www.cancer.net

National Cancer Institute*
The NCI is a component of the National Institutes of Health in the Department of Health and Human Services and provides current information about cancer and clinical trials as well as resources.
1-800-4-CANCER (1-800-422-6237)
TTY-1-800-332-8615 (for the deaf and hearing impaired)
www.cancer.gov

National Comprehensive Cancer Network*
NCCN creates clinical practice guidelines for use by patients, clinicians, and other health care decision-makers with the goal of improving the quality of oncology practice.
1-888-909-NCCN (1-888-909-6226)
www.nccn.org

*Genentech USA, Inc. is neither affiliated with nor endorses this organization.The information provided by Genentech USA, Inc. or this organization is meant for informational purposes only and is not meant to replace a physician's medical advice.

Indication

Avastin, in combination with carboplatin and paclitaxel (chemotherapy), is approved by the FDA for first-line treatment of people newly diagnosed with a common form of NSCLC (unresectable, locally advanced, recurrent, or metastatic non-squamous, non-small cell lung cancer).

Serious Side Effects

Avastin can result in the development of a potentially serious, and sometimes fatal, side effect called gastrointestinal (GI) perforation. GI perforation is the development of a hole in the stomach, small intestine, or large intestine. Symptoms may include abdominal pain, nausea, vomiting, constipation, and fever. Avastin therapy should be stopped if GI perforation occurs.

Treatment with Avastin can lead to slow or incomplete wound healing (for example, when a surgical incision has trouble healing or staying closed). In some cases, this event resulted in fatality. Stop Avastin for at least 28 days before voluntary surgery. Do not start Avastin for at least 28 days after surgery and until the surgical wound is fully healed. Avastin therapy should be stopped in patients who experience slow or incomplete wound healing.

Treatment with Avastin can result in serious and sometimes fatal bleeding. This includes coughing up blood, bleeding in the stomach, vomiting blood, bleeding in the brain, nosebleeds, and vaginal bleeding. People who have recently coughed up blood or have serious bleeding should not receive Avastin.

Please click here for additional important safety information.

Indication

Avastin, in combination with carboplatin and paclitaxel (chemotherapy), is approved by the FDA for first-line treatment of people newly diagnosed with a common form of NSCLC (unresectable, locally advanced, recurrent, or metastatic non-squamous, non-small cell lung cancer).

Possible Serious Side Effects and Additional Important Safety Information

What is the most important safety information I should know about Avastin?

Avastin can result in the development of a potentially serious, and sometimes fatal, side effect called gastrointestinal (GI) perforation. GI perforation is the development of a hole in the stomach, small intestine, or large intestine. Symptoms may include abdominal pain, nausea, vomiting, constipation, and fever. Avastin therapy should be stopped if GI perforation occurs.

Treatment with Avastin can lead to slow or incomplete wound healing (for example, when a surgical incision has trouble healing or staying closed). In some cases, this event resulted in fatality. Stop Avastin for at least 28 days before voluntary surgery. Do not start Avastin for at least 28 days after surgery and until the surgical wound is fully healed. Avastin therapy should be stopped in patients who experience slow or incomplete wound healing.

Treatment with Avastin can result in serious and sometimes fatal bleeding. This includes coughing up blood, bleeding in the stomach, vomiting blood, bleeding in the brain, nosebleeds, and vaginal bleeding. People who have recently coughed up blood or have serious bleeding should not receive Avastin.

What are the additional possible serious side effects of Avastin?

Serious side effects with Avastin include:

What are the most common side effects of Avastin?

The most common side effects of Avastin that occurred at >10% and at least twice the control rate include nosebleeds, headache, high blood pressure, inflammation of the nose, too much protein in the urine, taste change, dry skin, rectal bleeding, tear production disorder, back pain, and inflammation of the skin.

What should I do if I am pregnant or thinking of becoming pregnant?

You should not take Avastin while you are pregnant. If you stop Avastin, you should use a contraceptive for at least 6 months after your last dose before attempting to become pregnant.

What should I tell my health care provider before taking Avastin?

Avastin therapy may not be appropriate for certain people. Talk to your doctor if you: