Benefits and Risks of Avastin Therapy
Avastin, when used with intravenous 5-FU–based chemotherapy, is approved to treat first-line and second-line metastatic colorectal cancer (mCRC). There are benefits and risks of taking Avastin for your mCRC.
In studies, adding Avastin to IV 5-FU–based chemotherapy has been shown to significantly increase overall survival among patients with mCRC.
In studies, when people took Avastin and IV 5-FU–based chemotherapy instead of chemo alone:
The length of time people lived without their tumors growing or spreading increased significantly
More people saw their tumors shrink
Individual results may vary.
Studies have also shown that there are some serious side effects that may occur with Avastin therapy.
Side effects of Avastin in mCRC
See the tables below for select side effects that increased by 2% or more in patients who added Avastin to IV 5-FU–based chemotherapy.