IMPORTANT INFORMATION REGARDING COUNTERFEIT DRUG
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Downloadable Materials

We're here to support you, keep you informed, and help you better understand your Avastin therapy. These downloadable materials were created to do just that.

Avastin Quick Guide

Avastin Quick Guide

This useful guide explains how to get started with Avastin, how Avastin is designed to work, important safety information, side effects, and what to expect with Avastin therapy.

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Avastin Brochure

Avastin Brochure for Metastatic Colorectal Cancer (mCRC)

This informative brochure explains how Avastin is designed to work, the benefits of therapy, the risks of treatment, how often it is given, and more.

Avastin for Metastatic Colorectal Cancer (mCRC)

Metastatic Colorectal Cancer Guide

Brochure for Metastatic Colorectal Cancer (mCRC)

This guide provides specific information about metastatic colorectal cancer, practical tips to help you cope, and valuable support resources for you and your family.

Metastatic Colorectal Cancer (mCRC)

Doctor Visit Worksheet

Doctor Visit Worksheet

Make the most of your next doctor appointment. Use this worksheet to write down any questions you need answered, keep track of your treatment plan, and remember your refill dates for other medications you may be taking.

Doctor Visit Worksheet

Caregiver Guide

Caregiver Guide

As the caregiver, you're an important part of the health care team. Here's information to help you give your friend or family member the most effective care you can.

Caregiver Guide

What Does Avastin Treat?

Avastin is approved for:

  • Metastatic colorectal cancer (mCRC) when started with the first or second intravenous 5-FU–based chemotherapy for metastatic cancer

Possible Serious Side Effects

Everyone reacts differently to Avastin therapy. So it’s important to know what the side effects are. Although some people may have a life-threatening side effect, most do not.

Your doctor will stop treatment if any serious side effects occur. Be sure to contact your health care team if you have symptoms related to these side effects.

The most serious side effects (not common, but sometimes fatal):

  • Gastrointestinal (GI) perforation. A hole that develops in your stomach or intestine. Symptoms include pain in the abdomen, nausea, vomiting, constipation, or fever
  • Wounds that don’t heal. A cut made during surgery can be slow to heal or may not fully heal. Avastin should not be used for at least 28 days before or after surgery and until surgical wounds are fully healed
  • Serious bleeding. This includes vomiting or coughing up blood; bleeding in the stomach, brain, or spinal cord; and vaginal bleeding. If you recently coughed up blood or had serious bleeding, do not take Avastin

Other possible serious side effects:

  • Abnormal passage in the body. This forms from one part of the body to another and can sometimes be fatal
  • Stroke or heart problems. These include blood clots, mini-stroke, heart attack, and chest pain. These can sometimes be fatal
  • Severe high blood pressure. Blood pressure that severely spikes or shows signs of affecting the brain. Blood pressure should be monitored every 2 to 3 weeks while on Avastin and after stopping treatment
  • Nervous system and vision problems. Symptoms include high blood pressure, headache, seizure, sluggishness, confusion, and blindness
  • Kidney problems. These may be caused by too much protein in the urine and can sometimes be fatal
  • Infusion reactions. These may include difficulty breathing, chest pain, and excessive sweating. Your doctor or nurse will monitor you for signs of infusion reactions
  • Fertility issues for women. Avastin could cause a woman’s ovaries to stop working and may impair her ability to have children

Additional Safety Information

The most common side effects of Avastin are:

  • Nosebleeds
  • Headache
  • High blood pressure
  • Inflammation of the nose
  • Too much protein in the urine
  • Taste change
  • Dry skin
  • Rectal bleeding
  • Tear production disorder
  • Back pain
  • Inflammation of the skin

Avastin is not right for everyone. Talk to your doctor if you:

  • Are pregnant, may be pregnant, or are breast-feeding. Avastin may harm the fetus or a child that is nursing. If you stop Avastin, you should keep using birth control for at least 6 months after your last dose before trying to become pregnant
  • Are undergoing surgery. Don’t take Avastin for at least 28 days before or after surgery and until surgical wounds are fully healed

If you have any questions about your condition or treatment, talk to your doctor.

Please see full Product Information, including Serious Side Effects, for additional important safety information.