IMPORTANT INFORMATION REGARDING COUNTERFEIT DRUG
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Advice for Caregivers

Your role on the health care team

As the caregiver, you are a vital member of your friend or family member's health care team. Here are a few ways you can help as they begin treatment:

  • Write down any questions that either of you would like to ask the doctor
  • Offer to go with your family member or friend to medical appointments
  • Find out if there are any special instructions and treatment tips your doctor recommends
  • Keep track of medical information and paperwork
  • Note any changes in symptoms or side effects

By understanding when Avastin can be taken, you can help keep your friend or family member's treatment on track.

Caregiver Guide

Caregiver Guide

Learn more about caring for someone with metastatic cancer

Download the guide now

Communication is key

Metastatic cancer changes the patient's life, your life, and the lives of family members. As a caregiver, you should talk with your friend or family member about these changes. Here are a few tips for creating a healthy dialogue:

  • Ask if it's a good time to talk
  • Be supportive, listen, and don't interrupt
  • Practice what you'll say in advance
  • Speak from the heart
  • Remember that you can have more than one talk
  • Don't always say, "It'll be okay"

Talking with children

It can be difficult to tell children what's happened to mom or dad. But it's important to be truthful and speak openly about cancer at an age-appropriate level. Let them know that it's okay to be upset, angry, or scared. Listen to them and be sure to make time for your children in any way you can.

Find the support you need

Remember, support can come in different ways. You may find support through a friend, online, or from a professional organization. Here are some places to start your search for support:

CancerCare*
Provides free professional help to caregivers and people with cancer through counseling, education, information, referrals, and direct financial assistance.

Visit www.cancercare.org or call 1-800-813-HOPE (1-800-813-4673)

National Family Caregivers Association*
Educates, supports, empowers, and speaks up for those who care for loved ones with a chronic illness or disability.

Visit www.thefamilycaregiver.org or call 1-800-896-3650

*
Genentech USA, Inc. is neither affiliated with nor endorses this organization. The information provided by Genentech USA, Inc. or this organization is meant for informational purposes only and is not meant to replace a physician's medical advice.

What Does Avastin Treat?

Avastin is approved for:

  • Advanced nonsquamous non–small cell lung cancer (NSCLC) in combination with carboplatin and paclitaxel in people who have not received chemotherapy for their advanced disease

Possible Serious Side Effects

Everyone reacts differently to Avastin therapy. So it’s important to know what the side effects are. Although some people may have a life-threatening side effect, most do not.

Your doctor will stop treatment if any serious side effects occur. Be sure to contact your health care team if you have symptoms related to these side effects.

The most serious side effects (not common, but sometimes fatal):

  • Gastrointestinal (GI) perforation. A hole that develops in your stomach or intestine. Symptoms include pain in the abdomen, nausea, vomiting, constipation, or fever
  • Wounds that don’t heal. A cut made during surgery can be slow to heal or may not fully heal. Avastin should not be used for at least 28 days before or after surgery and until surgical wounds are fully healed
  • Serious bleeding. This includes vomiting or coughing up blood; bleeding in the stomach, brain, or spinal cord; and vaginal bleeding. If you recently coughed up blood or had serious bleeding, do not take Avastin

Other possible serious side effects:

  • Abnormal passage in the body. This forms from one part of the body to another and can sometimes be fatal
  • Stroke or heart problems. These include blood clots, mini-stroke, heart attack, and chest pain. These can sometimes be fatal
  • Severe high blood pressure. Blood pressure that severely spikes or shows signs of affecting the brain. Blood pressure should be monitored every 2 to 3 weeks while on Avastin and after stopping treatment
  • Nervous system and vision problems. Symptoms include high blood pressure, headache, seizure, sluggishness, confusion, and blindness
  • Kidney problems. These may be caused by too much protein in the urine and can sometimes be fatal
  • Infusion reactions. These may include difficulty breathing, chest pain, and excessive sweating. Your doctor or nurse will monitor you for signs of infusion reactions
  • Fertility issues for women. Avastin could cause a woman’s ovaries to stop working and may impair her ability to have children

Additional Safety Information

The most common side effects of Avastin are:

  • Nosebleeds
  • Headache
  • High blood pressure
  • Inflammation of the nose
  • Too much protein in the urine
  • Taste change
  • Dry skin
  • Rectal bleeding
  • Tear production disorder
  • Back pain
  • Inflammation of the skin

Avastin is not right for everyone. Talk to your doctor if you:

  • Are pregnant, may be pregnant, or are breast-feeding. Avastin may harm the fetus or a child that is nursing. If you stop Avastin, you should keep using birth control for at least 6 months after your last dose before trying to become pregnant
  • Are undergoing surgery. Don’t take Avastin for at least 28 days before or after surgery and until surgical wounds are fully healed

If you have any questions about your condition or treatment, talk to your doctor.

Please see full Product Information, including Serious Side Effects, for additional important safety information.