Avastin® (bevacizumab) is approved to treat glioblastoma (GBM) in adult patients whose cancer has progressed after prior treatment (recurrent or rGBM).
The benefits of Avastin therapy
In a clinical study, when people with recurrent glioblastoma took Avastin with chemotherapy (lomustine) instead of chemotherapy alone:
Avastin has not been proven to increase survival in patients with rGBM
- Tumor response is based on MRI and corticosteroid use. Tumor response rates were based on the Response Assessment in Neuro-Oncology (RANO) criteria
What are the side effects of Avastin in rGBM?
In a rGBM trial, all side effects were collected for people taking Avastin with lomustine or lomustine alone. Serious to life threatening blood clots in the veins of the body were seen in 5% of patients receiving Avastin with chemotherapy compared to 2% of patients receiving chemotherapy alone. In this study, 22% of people who took Avastin with lomustine stopped treatment compared to 10% of people who took lomustine alone. The side effects found in people taking Avastin and lomustine are similar to other trials.
Talk to your doctor about the benefits and risks of Avastin. To learn about the possible side effects of taking Avastin, visit the Side Effects page.
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FIND OUT HOW AVASTIN IS DESIGNED TO WORK
Avastin is a tumor starving therapy. Read more about how it’s designed to work.
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