The mechanism of action of Avastin has been elucidated in preclinical models. Its clinical significance is unknown.
Proposed effects | Potential effect on vessels | Potential impact on tumor |
---|---|---|
Anti-vascular | Regression of existing tumor vasculature[36-41] | Reduction of tumor size[37,42] |
Anti-angiogenesis | Inhibition of new and recurrent tumor vessel growth[37,43,44] | Inhibition of tumor growth[44-47] |
The mechanism of action of Avastin has been elucidated in preclinical models. Its clinical significance is unknown.
Avastin Prescribing Information. Genentech, Inc. 2022.
Avastin Prescribing Information. Genentech, Inc. 2022.
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Data on file. Genentech, Inc.
Data on file. Genentech, Inc.
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MMIT Analysis.
MMIT Analysis.
IQVIA Plantrak Corticosteroid Data.
IQVIA Plantrak Corticosteroid Data.
HLI lives database.
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